George Sanders was a sophisticated, witty and somewhat sinister presence in a string of film classics like Foreign Correspondent (1940), Rebecca (1940) The Picture of Dorian Gray (1945), and The Ghost and Mrs. Muir (1947), and his career reached its apex when he won the Best Supporting Actor Oscar for 1950 for his urbane performance as drama critic Addison deWitt in All About Eve. He ultimately lost interest and his film appearances descended into dreary hack work like The Kremlin Letter (1970) and Doomwatch (1972). His frequent bon mots about how bored he was seemed like world-weary drollness but they may have been a thinly-veiled cry for help, as he suffered from depression and at one time had 7 psychiatrists simultaneously treating him. On April 25, 1972 he took seven tubes of Nembutal in Barcelona, Spain and ended his life. His suicide note read : "Dear World: I am leaving because I am bored. I am leaving you with your worries in this sweet cesspool. Good luck"

Gig Young specialized in playing breezy nice guys who supported the male lead, and he painfuly longed for something better after winning Oscar nominations for Come Fill the Cup (1951) and Teacher's Pet (1958). He thought that he would finally ascend to the superstardom he aspired to when he won the Best Supporting Actor Oscar in 1969 for his role as a seedy dance promoter in They Shoot Horses, Don't They? but instead he settled into television work and forgettable movies like A Son-in-Law for Charlie McReady (1973) and A Black Ribbon for Deborah (1974). He might have reached the popularity he hoped for when he was cast as The Ringo Kid in Blazing Saddles (1974) but by then his drinking had overwhelmed him and he was replaced by Gene Wilder a few days after filming began because he was suffering from D.T.s on the set. He allowed his depression to consume him and he ultimately shot himself in the head after murdering his fourth wife on October 19, 1978. They had been married for three weeks.

Robin Williams was one of the most influential comic performers of his generation beginning with his breakthrough role in the 1978 TV series Mork & Mindy. He was a movie star coming out the gate in Popeye (1980) and The World According to Garp (1982) and hit his stride as an actor with Good Morning, Vietnam (1987), winning his first Oscar nomination in a showcase of his manic comedy styling occasionally given dramatic context within a forgettable plot set during the Vietnam war. He proved to be as popular in dramatic roles like Dead Poets Society (1989) and The Fisher King (1990) as he was in comedies like Alladin (1992) and Mrs. Doubtfire (1993) and his career peaked with his Oscar-winning performance as a compassionate psychiatrist in Good Will Hunting (1997). His output went into decline after that with heavy-handed schmaltz like Patch Adams (1998) and labored comedies like Death to Smoochy (2002) and the final decade-and-half of his career had far more lows than highs. He kept his clinical depression a secret to his fans and he shocked the world when he hanged himself in the middle of the night on August 11, 2014.

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